Sophisticated analytical instruments are used for quality evaluation and scientific validation to compliance the market demands. Recently, increase in demand of Curcuma longa has led to a high swing in small and medium food industry. The present review is devoted to an in-depth information on metabolite database of C. longa from different analytical techniques such as high-performance thin-layer chromatography (HPTLC), liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry and nuclear magnetic resonance. This work highlights different extraction methods, phytochemistry along with structure activity relationship, nutritional profiling, market viability and pharmacology of C. longa. The bioactives of C. longa depends on various factors such as plants growth, temperature, humidity, soil type, collection, drying and extraction process. These factors can contribute in quality evaluation of the food supplements if need to be included. The introduction of omics approaches can helpful to explore the quality and identification of potential lead of C. longa. The results could play an essential role in the area of food-phyto based profiling. Further, metabolomics techniques may provide an analytical platform by combination of different “omics” data sources for future research to food and herbal based products.