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Quantitative analysis, anti-diabetes bioactivities evaluation and mechanism investigation of acorn polysaccharides from three different species
來源:導入 閱讀量: 18 發(fā)表時間: 2025-11-05
作者: Longyi Ran, Jianing Du, Taiyu Zhang, Weimin Du, Zikun Lei, Zhengkun Han, Huiying Li
關鍵詞: Acorn polysaccharides Monosaccharide composition D-Mannuronic acid Type 2 diabetes
摘要:

The study investigated the effects of ethanol precipitation on the polysaccharide components obtained from 3 different oak acorns. The variables factors were ethanol precipitation times (1× or 2×), tree species (Quercus variabilis, Quercus aliena, Quercus dentata) and raw materials (whole acorn fruit or kernels). Through detections of acorn polysaccharide concentrations from different species and components analyses, we found that the second ethanol precipitation had a better extraction effect, and acorn polysaccharides were proved to be mainly composed of glucose, galacturonic acid, arabinose and galactose. Compared with other groups, the highest content of polysaccharides was proved to be extracted from Q. variabilis kernels, thus, acorn kernels should be suggested as the proper material for the extraction of acorn polysaccharides. Interestingly, acorn polysaccharides functionally alleviated liver and kidney damages in type 2 diabetes mice, they also had noticeable hypoglycemic effects and regulated insulin secretion, particularly in combination with metformin and D-mannuronic acid.

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