領(lǐng)學(xué)術(shù)科研之先,創(chuàng)食品科技之新
—— 中國(guó)食品雜志社
期刊集群
Application of natural -glucans as biocompatible functional nanomaterials
來(lái)源:食品科學(xué)網(wǎng) 閱讀量: 409 發(fā)表時(shí)間: 2019-12-30
作者: Xiaojie Li, Peter Chi Keung Cheung
關(guān)鍵詞: β-Glucans, Biocompatibility, Biopharmaceuticals,
摘要:

Naturally-occurring β-glucans are mostly investigated for their antitumor activity and immunomodulatory

property. They have been widely regarded as a natural source for functional foods and

pharmaceuticals. However, the physico-chemically stable and biocompatible properties of β-glucans

are rarely explored as a coating material for nanomaterials to overcome the problems of aggregation

and cytotoxicity. This article reviews on the exploration of β-glucans, in particular those derived from

mushrooms, as a natural coating material to modify the surface properties of bioactive substances as

a relatively simple and cost-effective strategy to produce stable and biocompatible nanohybrids used

for biopharmaceutical use. It is envisaged that such β-glucan-based coating method will provide new

opportunities to design biocompatible functional nanomaterials for wider clinical applications.

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